Pioneering RNAi Solutions,
One Knockdown at a Time
Making RNAi research simpler, smarter, and more effective
Pioneering RNAi Solutions,
One Knockdown at a Time
At ADViRNA, our mission is to make gene knockdowns simple, efficient, and fast

Founded in 2007 by Dr. Alexey Wolfson and Dr. Anastasia Khvorova, ADViRNA was built on the vision of creating high-performance, nucleic acid–based technologies to drive therapeutic discovery.
From the start, our mission has been to give researchers the tools to study and manipulate gene activity with precision. Today, ADViRNA is a trusted partner for academic labs, emerging biotech companies, and global pharma teams. Our boutique CRO model keeps us nimble—offering rapid turnaround, transparent collaboration, and programs tailored to your scientific and budget goals.
We bring deep expertise in RNAi design, synthesis, and screening, supporting projects from exploratory research through preclinical candidate validation. Every experiment is guided by data and shaped by ongoing scientific dialogue, so results move discovery forward in a meaningful way. At ADViRNA, we believe innovation comes from partnership. By combining our expertise with your vision, we help turn complex challenges into clear, actionable results.
Trusted by Global Leaders in RNA Therapeutics
“We have contracted ADViRNA for designing, synthesizing, and screening several ASOs and siRNAs targeting specific alleles. In addition to the quality of work, the customer service stands out as being second to none. Working with ADViRNA has helped us make significant strides in our research program.”
Dr. Daniel Davis | Director and Associate Research Professor – University of Missouri
“GenKardia called on ADViRNA to assist with lead identification for one of our oligo-based programs. To say the least, I could not be happier with this choice. ADViRNA is much MUCH more than a CRO. They took time to understand our needs, discussed our science and therapeutic approach, developed a clever oligo screen, and (the best part) identified a lead! Furthermore, they are always there for our questions and/or brainstorming on oligo drug development strategy (they are truly scientists at heart). In sum, ADViRNA is brilliant in the field, generous with their time, and incredibly friendly. I cannot recommend them enough for anyone’s oligo drug develop program.”
David C. Zebrowski | Founder and CEO – GenKardia Inc.
Integrated RNAi Services, From Concept to Candidate

Strategic Experimental Planning

Custom Oligonucleotide Synthesis

Proprietary Oligonucleotide Design

High-Throughput Screening

Custom Assay Development

Biodistribution Analysis

Precision Data Analysis

In Vivo Study Coordination
We offer partnerships that evolve with your needs
Our boutique CRO model ensures direct access to our scientific staff throughout the entire project lifecycle—from sequence design to data interpretation. We adapt to your goals and timelines with scalable, budget-conscious programs that deliver results without compromising scientific rigor.
Driving Discovery Forward
Whether you’re an academic lab, an emerging biotech, or a growing pharma team, let us help you move discovery forward—faster, smarter, and with true scientific partnership from start to finish.
Driving Discovery Forward
Whether you’re an academic lab, an emerging biotech, or a growing pharma team, let us help you move discovery forward—faster, smarter, and with true scientific partnership from start to finish.
