Our Expertise
Comprehensive oligonucleotide workflows, from in-house synthesis and quality control to advanced screening and validation
Our Expertise
Comprehensive oligonucleotide workflows, from in-house synthesis and quality control to advanced screening and validation
Technical Capabilities
We maintain a robust suite of in-house equipment that enables rapid, flexible, and high-quality execution of molecular and cellular workflows:
ThermoFisher QuantStudio Systems
For high-throughput qPCR and TaqMan-based analysis
SpectraMax
iD5 Plate Reader
For absorbance, fluorescence, and luminescence readouts
Opentrons OT-2
Liquid Handler
For automated pipetting, plating, and assay workflows
Agilent 6125C
LC-MS System
For oligonucleotide quality control and analytics
Biolytic Dr. Oligo
48 Synthesizer
For in-house synthesis of siRNAs and ASOs with common chemical modifications and conjugations
Assay Capabilities
Every experiment at ADViRNA is treated as a unique project. We adapt plate formats, oligo concentrations, screen sizes, and timepoints to suit your biological system and budget. Our scientific team works closely with you to weigh the pros and cons of each approach and ensure optimal study design.
PCR / qPCR
ELISA
Western Blot
HYBRID-ON™
Immunoprecipitation / Pull-Downs
Gel Electrophoresis
Diverse Applications, Disease-Agnostic Approach
Cytotoxicity & Viability Assays
Assess on-target and off-target effects of candidate oligonucleotides by measuring cell death or proliferation across relevant cell models
Flow Cytometry
Profile cellular responses to siRNA/ASO treatment by quantifying surface and intracellular markers, enabling detailed immune or phenotypic readouts
Functional Immune Assays
Evaluate immunostimulatory activity of oligos by detecting cytokine release, immune cell activation, or subset-specific responses to treatment
Additional Assays Available Upon Request
We’re happy to discuss custom assays, formats, or adaptations based on your needs.
Additional Assays Available Upon Request
We’re happy to discuss custom assays, formats, or adaptations based on your needs.